The Agora and E3 teams are using SASS and Compass, and probably others are now or will in the future. It would simplify this workflow if ResourceLoader had support for this.
http://www.phpsass.com/ would be one option for implementing this. However, it is not clear whether it has complete Compass support. See http://stackoverflow.com/a/15045473/47773
Version: 1.21.x
Severity: enhancement
See Also:
https://bugzilla.wikimedia.org/show_bug.cgi?id=40964